According to a new series of studies on animals, when men and women smoke marijuana together, its the females who may get more high.
“The study’s application to humans is largely unreasonable,” Dr. Jordan Tishler who has worked as a cannabis specialist for more than 20 years (and was not involved in the study) said to Fatherly. “On a behavioral level, mice and humans have very little in common.”
“Females seem to be more vulnerable, at a neurochemical level, in developing an addiction to cannabis,” said study coauthor Liana Fattore, a Senior Researcher at the National Research Council of Italy and President of Mediterranean Society of Neuroscience.
She added, “Interactions between the endocannabinoid system and the brain level of dopamine—the neurotransmitter of “pleasure” and “reward”—are sex-dependent.”
It may be Estradiol, a form of estrogen that drives sexual function and can influence how rats respond to being intoxicated.
