Earlier this month the National Institute on Drug Abuse (NIDA) has announced that it has set the standardized THS dose for cannabis research.

According to Marijuana Moment, the dose is set at five milligrams and the requirement has taken effect immediately.

“Inconsistency in the measurement and reporting of THC exposure has been a major limitation in studies of cannabis use, making it difficult to compare findings among studies. A standardized measure of THC in cannabis products is necessary to advance research by providing greater comparability across studies of both its adverse effects and potential medical uses,” read the NIDA Notice of Information excerpt.

NIDA has said that the five-milligram standard unit was selected following extensive stakeholder input, expert consultation, and a request for information from the general public.

NIDA recognized that “the same quantity of THC may have different effects” depending on a number of variables, including the method of administration, other ingredients in the product, an individual’s genetic make-up and tolerance levels, and more. Additionally, the notice clarified that the newly standardized THC unit does not limit the quantity of THC permissible in cannabis research, only the way in which investigators must record and report their work.

“It is not the intent of this Notice to prescribe the quantity of THC that is permissible for use in research projects. Indeed, investigators are free to use more or less than 5mg of THC as appropriate for their study,” the notice states. “However, for applicable studies, investigators will be required to report the quantity of THC using the standard unit. Investigators may also report the quantity of THC in other units (e.g., milligrams) as appropriate.”


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